Least sedating second generation antihistamine

11-Jul-2019 08:22

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Nevertheless, a considerable proportion of patients do not respond sufficiently to NSAHs.

According to Humphreys and Hunter up to 40% of patients with CU may not achieve good control with antihistaminic therapy [].

They reported that out of 390 CU patients who were treated with antihistamines 44% responded well, 29% became asymptomatic, and 15% showed partial improvement.

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Urticaria and angioedema lasting more than 6 weeks have been designated as chronic urticaria (CU).

"In some studies we reviewed, some people actually experienced more sedation with the newer, nonsedating formulas than with the older, sedating products.

Urticaria is characterised by weals (hives) or angioedema (swellings, in 10%) or both (in 40%). The name urticaria is derived from the common European stinging nettle 'Urtica dioica'.

This sedating activity is sometimes used in managing conditions such as eczema where sleep maybe disturbed due to pruritus.

Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.

Urticaria and angioedema lasting more than 6 weeks have been designated as chronic urticaria (CU).

"In some studies we reviewed, some people actually experienced more sedation with the newer, nonsedating formulas than with the older, sedating products.

Urticaria is characterised by weals (hives) or angioedema (swellings, in 10%) or both (in 40%). The name urticaria is derived from the common European stinging nettle 'Urtica dioica'.

This sedating activity is sometimes used in managing conditions such as eczema where sleep maybe disturbed due to pruritus.

Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.

Urticaria can affect any site of the body and tends to be distributed widely.